MabVax Therapeutics Holdings, Inc. (NASDAQ: MBVX) is a biopharmaceutical company developing monoclonal antibody (mAb) products for the treatment of cancer. The company’s novel mAb technology involves a unique twist on the generation of fully human mAbs as they are derived from patients vaccinated with an anti-cancer vaccine, as opposed to antibodies produced in mice or…
I’ve been a stock analyst for a pretty long time – going on 16 years now. I’ve picked some big winners and some big losers. One thing I noticed, I seem to have better luck in CNS disorders than say, wound care! Acadia Pharmaceuticals, Auspex Pharma, Neurocrine Bio, and Cynapsus Therapeutics were all small-cap biopharma…
On August 26, 2016, Can-Fite BioPharma, Ltd (CANF) provided a financial update for the six month period ending June 30, 2016. The company also provided an update on its pipeline, which I believe remains meaningfully undervalued. Can-Fite’s market capitalization today is a measly $33 million, and roughly one-third of that is cash. Below is a…
Diabetes is a significant public health crisis. The number of American’s with diabetes is soaring and will soon eclipse 30% of the population. Independent studies find that the vast majority of Type-2 diabetic patients do not achieve recommend A1C levels of less than 7% on insulin therapy. Compliance, complexity of dosing, and discretion of disease…
BrainStorm Cell Therapeutics, Inc. (NASDAQ: BCLI) is biopharmaceutical company developing adult stem cell-based therapies for a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson’s disease (PD). The company’s NurOwn® technology is based on the use of mesenchymal stem cells (MSCs) that are engineered ex vivo to express increased amount…
The psychiatric community seems on the verge of a medical breakthrough to treat depression, or more specifically, major depression that is resistant to traditional antidepressants like Prozac®, Paxil®, and Zoloft®. The focus is on the NMDA-receptor, and it stems from a recent discovery that ketamine, the psychiatric “party-drug” of the 70’s, is both highly effective…
Oryzon Genomics (MADX: ORY) is a clinical stage biopharmaceutical company headquartered in Barcelona, Spain. In December 2015, I provided a detailed overview of the company for investors (download the 19-page report). Oryzon is a leader in the development of epigenetics-based therapeutics. Epi is Greek for above, and genetics is the study of genes, heredity, and…
Safety & Efficacy Tested In 10 Clinical Trials To Date Investors interested in RedHill Biopharma Ltd. (RDHL) are keeping a close watch on three pending catalysts. These include the initiation of the confirmatory Phase 3 program with RHB-105, a potential new standard-of-care for H. pylori infection, interim DSMB analysis from the Phase 3 study with…
CanFite Biopharma Ltd. (CANF) is currently conducting a Phase 2 clinical study with CF102 for the treatment of hepatocellular carcinoma (HCC). The focus of the study is to test CF102, a selective A3 adenosine receptor (A3AR) agonist, as a second-line treatment of advanced HCC in subjects with Child-Pugh B cirrhosis. The 78-patient trial is currently…
The psychiatric community may be on the verge of a paradigm shift when it comes to treating the severely depressed. New treatment options are desperately needed, because what is clear today is that generic antidepressants do not work for many patients. A 2007 report by the Agency for Healthcare Research and Quality (AHRQ) compared the…